01:694:214
Introduction to Molecular Biology Research (3)
Basic principles and methods of research, followed by a research project: analyses of molecular clones from eukaryotic cDNA libraries. Description of research opportunities
available to undergraduates at the university.
Prerequisites: For first-year students only who have placed out of General Biology (01:119:115,116, and 117) with AP credits, and 01:160:161 or 01:160:163. Corequisite: 01:160:162 or 164.
|
01:694:215
Honors Introduction to Molecular Biology and Biochemistry Research (4)
Basic principles and methods of research, followed by a research project: isolation and analyses of transcriptional regulatory mutants in yeast. Description of research opportunities that are available to undergraduates at the university.
Prerequisite: Limited only to first-year SAS Honors Program or Honors College students who have placed out of General Biology (01:119:115,116, and 117) with AP credits. Corequisites: 01:160:161 or 01:160:163 (or AP credits) and 01:640:135 or 01:640:151 (or AP credits).
|
01:694:230
Analytical Methods in Biology (3)
Mathematical methods and tools to analyze and interpret
biological and biomedical data, including probability theory; Bayes Theorem;
the binomial, Poisson, and normal distributions; limit theorems; error analysis;
tests of statistical significance; parameter estimation; curve fitting;
sampling techniques; random number generation; and Monte Carlo methods. Analysis of sequencing and microarray data, such as sequence alignment,
phylogeny inference, population structure, selection, and human migration.
Prerequisites: 01:119:115-116 and 01:640:135 or 151.
|
01:694:281,282
Sophomore Laboratory Research (2-6,2-6). 281 is Fall, 282 is Spring
Research project in the laboratory of a faculty member. Written report of research carried out during each semester required. Credits in this course cannot be used toward the required research credits for laboratory option. Students must complete a special permission form and have it signed by their research advisor and then send the signed form to the Undergraduate Director (Sam Gunderson) before they can register for the course.
|
01:694:283
01:694:283 Undergraduate Laboratory Research (2-6). Summer semester
Independent research project in the laboratory of a faculty member. A written report of research carried out during each semester required by the end of each semester.
Typically for rising Juniors and Seniors. Students must complete a special permission form and have it signed by their research advisor and then send the signed form to the Undergraduate Director (Sam Gunderson) before they can register for the course.
Prerequisite: Students must complete a special permission form and have it signed by their research and MBB faculty mentors before they can register of the course.
|
01:694:301
Introductory Biochemistry and Molecular Biology (3)
Chemistry and metabolism of proteins, carbohydrates, lipids, nucleic acids, and other biologically important compounds.
Prerequisite: 01:160:209 or 307. Not for students majoring in molecular biology and biochemistry. Credit not given for both this course and 01:694:407, 11:115:301, or 11:115:403.
|
01:694:313
Introductory Biochemistry Laboratory (1)
Techniques used in research, clinical, and food laboratories, including
tests of biological materials, methods of separation, and determination
of enzyme activities.
Lab. 3 hrs. Pre- or corequisite: 01:694:301. Not for students majoring in molecular biology and biochemistry.
|
01:694:315
Introduction to Molecular Biology and Biochemistry Research (3)
Basic principles and methods of research, followed by a research
project: analyses of molecular clones from eukaryotic cDNA libraries.
Description of research opportunities at the university available to
undergraduates.
Pre- or corequisites: 01:119:115,116, and 117; and 01:160:161-162, 171 or 01:160:163-164, 171. Credit not given for both this course and 01:447:315, 01:694:214, 215, or 316. Open only to MBB majors.
|
01:694:316
Honors Introduction to Molecular Biology, Biochemistry, Genetics Research (4)
Basic principles and methods of research in molecular biology, biochemistry, and genetics, followed by a research project: isolation
and analyses of transcriptional regulatory mutants in yeast. Description of research opportunities that are available to undergraduates at the university.
Prerequisites: 01:119:116 and (01:160:162 or 01:160:164). For MBB or genetics majors only or those planning on being MBB or genetics majors. Special permission required.
|
01:694:381,382
Undergraduate Laboratory Research (3-6,3-6). 381 is Fall, 382 is Spring
Research project in the laboratory of a faculty member. Written report of research carried out during each semester required. Students must complete a special permission form and have it signed by their research advisor and then send the signed form to the Undergraduate Director (Sam Gunderson) before they can register for the course.
|
01:694:383
Molecular Biology and Biochemistry Seminar: Careers in Science (1)
Discussion of career options in the life sciences, finding a research laboratory, performing literature searches, reading a scientific
paper, and creating posters and abstracts. This course should be taken in the
beginning of the third year.
Open to MBB majors only.
|
01:694:384
Undergraduate Laboratory Research (1-6). Summer semester
Independent research project in the laboratory of a faculty member. A written report of research carried out during each semester required by the end of each semester.
For rising Seniors. Students must complete a special permission form and have it signed by their research advisor and then send the signed form to the Undergraduate Director (Sam Gunderson) before they can register for the course.
For rising Seniors. Students must complete a special permission form and have it signed by their research advisor and then send the signed form to the Undergraduate Director (Sam Gunderson) before they can register for the course.
|
01:694:385
MBB Research and Writing (3)
Research project in the laboratory of a faculty member.
Seminar on science communication. Written and oral reports of research carried
out during the semester required.
Prerequisites: MBB majors only. Students need a GPA of 2.8 or better to enroll in research.
|
01:694:390
Introductory Computational Biology (3)
Disciplines of biochemistry and molecular biology and genomics all include collection and analysis of large data sets. Hands on use in a computer lab will permit students to learn and apply computer languages such as Python and R to analyze large data including for example DNA mutations and structural variations (SVs), RNA-seq and ChIP-seq as part of understanding genes and gene regulation.
Prerequisite: 01:447:380 or 01:447:384
|
01:694:395
Biochemistry for Life Sciences (3)
The course is intended for life science majors and takes a holistic approach to Biochemistry. You will learn the basics of proteins, enzymology, nucleic acids and metabolism and use these as foundations to discuss exemplary metabolic pathways for their importance to homeostasis and, when dysregulated, to disease including observable phenotypes and what current strategies are used to treat these disorders. Coursework will consist of quizzes, homework, exams and one graded paper.
Prerequisites: 01:160:307 or 01:160:315
|
01:694:407
Biochemistry (3)
Protein structure and function, structure of lipids, membranes and carbohydrates, catalysis of biochemical reactions, intermediary metabolism, oxidative phosphorylation, membrane transport, lipid metabolism, signal transduction, photosynthesis, protein secretion, targeting and turnover, nitrogen, amino acid, and nucleotide metabolism.
Pre- or corequisites: 01:160:307-308 or 315-316. Credit not given for both 01:694:407 and 01:694:301, 11:115:301, or 11:115:403.
|
01:694:408
Molecular Biology and Biochemistry (3)
Disciplines of biochemistry and molecular biology as
interlocking and mutually complementary fields of study. Lectures on structure
of DNA, RNA, recombinant DNA approaches, DNA replication, repair and
recombination, mobile genetic elements, transcription, gene regulation, RNA
splicing, translation, and viral gene expression.
Prerequisite: 01:694:407 or 01:694:301 or 01:694:395 or 11:115:403. Credit not given for both 01:694:408 and 01:146:478 or 11:126:481.
|
01:694:411
Molecular Pathways and Signal Transduction (3)
Lectures and discussion of current research areas of advanced molecular
and structural biology: transcription, posttranscriptional regulation,
cell cycle, neurobiology, protein folding, macromolecular recognition,
and molecular virology.
Pre- or corequisites: 01:694:407 and 408, or 01:447:384-385 or 11:115:403-404 or 11:126:481.
|
01:694:412
Proteomics and Functional Genomics (3)
Survey of modern techniques of protein biochemistry, bioinformatics, proteomics, and functional genomics, including basic concepts of protein structure and function, protein folding, protein characterization and purification, enzyme kinetics, NMR and X-ray crystallography, mass spectrometry, yeast two hybrid, and various techniques and approaches to functional and structural genomics.
Prerequisites: [(01:694:301 OR 01:694:407 OR 01:694:395) AND (01:447:380) OR (01:447:384)]
|
01:694:413
Chromatin and Epigenomics (3)
Introduction to chromatin dynamics, particularly the
structural and biochemical modifications of chromatin that underlie epigenetic
states and their effects on gene expression and development.
Pre- or corequisites: Prerequisite: 01:694:408 or 01:146:478 or 01:447:385.
|
01:694:420,421
Special Topics in Molecular Biology and Biochemistry (3,3)
Directed reading and discussion of
selected topics of special interest in molecular biology and biochemistry.
Topics will vary according to semester and/or instructor.
Pre- or corequisites: [(01:694:301 or 01:694:407) and (01:447:380 or (01:447:384)] or equivalent.
|
01:694:481,482
Advanced Undergraduate Laboratory Research (BA, BA). 481 is Fall, 482 is Spring.
Research
project in the laboratory of a faculty member. A written report of research
carried out during each semester is required. Oral presentations of student
research are required in 01:694:484.
|
01:694:484
Molecular Biology and Biochemistry Seminar: Research Presentations (1)
Oral presentation of student's own research results and the research
interests of the laboratory with which the student is associated.
Presentation at a required poster session.
Students should take this course in the spring semester of their senior year. MBB majors only.
|
01:694:489,490
Literature Research in Molecular Biology and Biochemistry (1-3,1-3)
Literature research projects on a selected subject under the direction of a faculty member. A written report of research carried out during each semester is required. Oral presentations of student research are required in 01:694:484. This course is rarely used, therefore contact the Undergraduate Director if you are considering to take this course.
Prerequisites: 01:694:214, 215 or 315, 407, 408, and 383.
|
01:694:492
Gene Regulation: Clocks to Cancer (3)
Explanation of MBB as an experimental science and how molecular biologists know what they know. Covers all aspects of gene regulation from transcription to protein modification to explain how 25,000 human genes can make millions of different protein isoforms and mRNA and ncRNA. Mechanisms of molecular clocks and cancer addressed in terms of gene regulation complexity,feedback loops and rate-limiting steps with emphasis on the methods, experimental design,
Prerequisites:(01:694:407 BIOCHEM) OR (01:447:384 GEN ANALY) OR (11:126:481 MOLE GEN) OR (11:115:403 GEN BIOCHEM) OR (01:694:395 BioChem LS)
|
01:694:495,496
Honors Laboratory Research (BA)
Two-semester-long Honors research project in the laboratory of a faculty member. In the Fall semester, 01:694:495 students are required to attend a seminar each week on writing a thesis and preparing an oral thesis presentation. In the Spring semester, students take 01:694:496 where they complete their Honors thesis and give their oral presentation to their honors committee..
|
