01:694:281,282Sophomore Laboratory Research (1-6,1-6) Research project in the laboratory of a faculty member. Written report of research carried out during each term required. Credits in this course cannot be used toward the required research credits for laboratory option.

01:694:301Introductory Biochemistry and Molecular Biology (3) Chemistry and metabolism of proteins, carbohydrates, lipids, nucleic acids, and other biologically important compounds. Prerequisites: 01:160:209 or 307-308. Not for students majoring in molecular biology and biochemistry.

01:694:313Introductory Biochemistry Laboratory (1) Techniques used in research, clinical, and food laboratories, including tests of biological materials, methods of separation, and determination of enzyme activities. Lab. 3 hrs. Pre- or corequisite: 01:694:301. Not for students majoring in molecular biology and biochemistry.

01:694:315Introduction to Molecular Biology and Biochemistry Research (3) Basic principles and methods of research, followed by a research project: analyses of molecular clones from eukaryotic cDNA libraries. Description of research opportunities at the university available to undergraduates. Pre- or corequisites: 01:119:101-102; 01:160:307-308 or 315-316.

01:694:381,382Undergraduate Laboratory Research (3-6,3-6) Research project in the laboratory of a faculty member. Written report of research carried out during each term required.

01:694:407-408Molecular Biology and Biochemistry (3,3) Disciplines of biochemistry and molecular biology as interlocking and mutually complementary fields of study. First term: protein structure and function, structure of DNA, RNA, lipids, membranes and carbohydrates, catalysis of biochemical reactions, intermediary metabolism, oxidative phosphorylation, recombinant DNA approaches, DNA replication, repair and recombination, mobile genetic elements. Second term: transcription and gene regulation, RNA splicing, translation, viral gene expression, membrane transport, lipid metabolism, signal transduction, photosynthesis, protein secretion, targeting and turnover, nitrogen, amino acid, and nucleotide metabolism. Pre- or corequisites: 01:160:307-308 or 315-316.

01:694:411Molecular Pathways and Signal Transduction (3) Lectures and discussion of current research areas of advanced molecular and structural biology: transcription, posttranscriptional regulation, cell cycle, neurobiology, protein folding, macromolecular recognition, molecular virology. Prerequisites: 01:694:407-408 or 01:447:384-385 or 11: 115:403-404 or 11:126:481.

01:694:412Proteomics and Functional Genomics (3) Survey of modern techniques of protein biochemistry, bioinformatics, proteomics, and functional genomics, including basic concepts of protein structure and function, protein folding, protein characterization and purification, enzyme kinetics, NMR and X-ray crystallography, mass spectrometry, and various techniques and approaches to functional and structural genomics. Prerequisites: 01:694:407 and 01:447:380 or permission of instructor. Corequisite: 01:694:408 or permission of instructor.

01:694:481,482Advanced Undergraduate Laboratory Research (3-6,3-6) Research project in the laboratory of a faculty member. Written report of research carried out during the fall term required; senior thesis required in the spring term. Oral presentation of student research presented in 01:694:483,484. Pre- or corequisites: 01:694:315, 407-408, and 483,484.

01:694:483,484Seminar in Molecular Biology and Oral presentation of student`s own research results and the research interests of the laboratory with which the student is associated. Discussion of career options in the fall, and a required poster session of student research in the spring. Thesis required. Pre- or corequisites: 01:694:315, 381,382, and 407-408; or 481,482, 489,490, or 495,496.

01:694:489,490Literature Research in Molecular Biology and Biochemistry (3,3) Literature research projects on a selected subject under the direction of a faculty member. Students write a thesis and present their research results in 01:694:483,484. Prerequisites: 01:694:315, 407-408, and 483,484.

01:694:492Gene Regulation in Cancer and Development (3) Advanced molecular studies of modern eukaryotic genetic and developmental issues. Experimental approaches focusing on current research questions, including control of gene expression in yeast, Drosophila and C. elegans�developmental genetics, and molecular biology of cancer and oncogenesis. Pre- or corequisite: 01:694:407-408 or 01:447:384-385 or 11:115:403-404 or 11:126:481.

01:694:495,496Honors Laboratory Research (6,6) Honors research project in the laboratory of a faculty member. Oral presentation of student research presented in 01:694: 483,484. Honors thesis and oral presentation required. Pre- or corequisites: 01:694:315, 407-408, and 483,484.