01:146:201,202 Independent Study in Cell Biology and Neuroscience (1-3,1-3) Independent study under the direction of a member of the faculty. Written report required.� Prerequisites: Permission of department and a cumulative grade-point average of 2.8 or better. May not be used to fulfill a laboratory requirement.

01:146:245 Fundamentals of Neurobiology (3) Introduction to the biology of the nervous system. Topics covered include nerve cell signaling, sensory and motor systems, and higher brain processes. Prerequisites: 01:119:101-102.

01:146:270 Fundamentals of Cell and Developmental Biology (3) Principles of cell biology. Structure, function, and macromolecular organization of cellular organelles. Prerequisites: 01:119:101-102.

01:146:307,308 Research in Cell Biology and Neuroscience (1-3,1-3)

Laboratory research on original problem under the direction of a member of the faculty. Written report required.

Prerequisites: Permission of department and a cumulative grade-point average of 2.8 or better.

01:146:322 Animal Histology (4)

Structure of the tissues and organs of the animal body.

Lec. 3 hrs., lab. 3 hrs. Prerequisite: 01:146:270.

01:146:328 Human Parasitology (3)

Discussion of the cell biology, epidemiology, pathogenesis, and clinical manifestations of human parasitic diseases.

Lec. 3 hrs. Prerequisites: 01:119:101-102.

01:146:329 Human Parasitology Laboratory (1)

Laboratory to accompany 01:146:328.

Lab. 3 hrs. Pre- or corequisite: 01:146:328.

01:146:356 Systems Physiology (3)

Comprehensive study of the principal organ systems of laboratory animals and humans.

Prerequisites: 01:119:101-102 and 01:160:161-162, 171. Credit not given for both this course and 11:067:300.

01:146:357 Systems Physiology Laboratory (1) Laboratory to accompany 01:146:356.� Lab. 3 hrs. Pre- or corequisite: 01:146:356.

01:146:405 Honors Seminar (3) Development of communication and written skills needed by professionals in cell biology and neuroscience. Oral reports, written�papers, and discussion of topics of current interest in the field.� Prerequisite: Permission of department. Open only to senior honors students.

01:146:406-407 Research in Cell Biology and Neuroscience (1-4,1-4) Research under the direction of a member of the departmental faculty. Written report required. Prerequisites: Permission of instructor and a cumulative grade-point average of 2.8 or better. Open only to students majoring in cell biology and neuroscience.

01:146:408-409 Honors Research (3-6,3-6) Research project under the direction of a departmental faculty member. Written report and oral presentation required.
Prerequisites: Permission of department. Open only to seniors majoring in cell biology and neuroscience who meet the requirements for the departmental honors program.

01:146:445 Advanced Neurobiology I (4)

Advanced concepts in neurobiology focusing on cellular and molecular aspects of neuronal signaling, including ion channel gating, sensory transduction, and transmission across chemical and electrical synapses.

Prerequisite: 01:146:245.

01:146:446 Advanced Neurobiology Laboratory I (3) Advanced laboratory methods in neurobiology. Electrophysiological and immunochemical techniques to explore the structural and functional features of nerve cells.� Prerequisites: 01:146:445 and permission of instructor.

01:146:448 Advanced Neurobiology Laboratory II (3) Advanced laboratory methods in molecular neurobiology.� Study of neuronal differentiation, neurite outgrowth, and neuronal protein trafficking using molecular biological, cell biological, and biochemical techniques.
Prerequisites: 01:146:445 and permission of instructor.

01:146:450 Endocrinology (3)

Endocrinology and neuroendocrinology of animals, including humans. The structure and function of the endocrine glands, including the hypothalamus, and the biosynthesis and chemistry of hormones.

Prerequisites: 01:119:101-102. Recommended: Courses in physiology and organic chemistry. Open to juniors and seniors only. Credit not given for both this course and 11:067:450.

01:146:464 Topics in Cell Biology and Neuroscience (3) Directed readings and discussion of selected topics in cell biology and neuroscience. Prerequisites: 01:146:245 and 270.

01:146:470 Advanced Cell Biology (3) Advanced concepts of cell biology focusing on the molecular organization of cells, including internal membranes and synthesis of macromolecules, the cell nucleus, the cell cycle, cytoskeleton, cell-cell adhesion and the extracellular matrix, and signal transduction.
Prerequisite: 01:146:270. Credit not given for both this course and 01:119:370 or 378 or 01:146:370.

01:146:471 Advanced Cell Biology Laboratory (3) Advanced laboratory methods in cell biology. Emphasis on light and electron microscopy, imaging, immunochemical techniques, tissue culture, and methods of identifying and separating macromolecules.� Prerequisites: 01:146:470 and permission of instructor.

01:146:472 Advanced Developmental Biology (3)

Molecular biology of early development, morphogenesis, organogenesis, tissue interactions, and genetic control of cellular differentiation.

Prerequisite: 01:146:270.

01:146:473 Advanced Developmental Biology Laboratory (3)

Advanced laboratory methods in developmental biology. Designed to introduce students to techniques of obtaining and handling gametes and experimental manipulation of embryos. Focus on sea urchin, frog, zebra fish, and chick.

Prerequisites: 01:146:472 and permission of instructor.

01:146:474 Immunology (3) Fundamental principles of immunology with emphasis on antibody�formation, immunoglobulin molecules and genes, hypersensitivity reactions, and the cellular basis for the immune response. Prerequisites: 01:119:101-102 and 01:447:380 or 384. Recommended: 01:447:390.

01:146:475 Laboratory in Immunology (1) Biochemical and molecular analysis of immune cell function. Application of immunological techniques to the examination of normal and diseased states.� Pre- or corequisite: 01:146:474.

01:146:478 Molecular Biology (3) Structure and function of macromolecules, recombinant DNA technology, and study of genes and their regulation at the molecular and cellular levels. Prerequisites: 01:160:307-308. For juniors and seniors only. Credit not given for both this course and 01:694:408 or 11:126:481.