01:146:245Fundamentals of Neurobiology (3) Introduction to the biology of the nervous system. Topics covered include nerve cell signaling, sensory and motor systems, and higher brain processes. (Formerly 01:119:245) Prerequisites: 01:119:101-102.

01:146:270Fundamentals of Cell and Developmental Biology (3) Principles of cell biology. Structure, function, and macromolecular organization of cellular organelles. Prerequisites: 01:119:101-102. Credit not given for both this course and 01:119:370 or 378 or 460.

01:146:302Computers in Biology (3) Application of the computer in analysis of biological data. Includes programming techniques and simulations of biochemical, physiological, genetic, ecological, medical, and evolutionary phenomena. (Formerly 01:119:302) Prerequisites: 01:119:101-102; 01:160:161-162; and 01:640:135, 138.

01:146:312Human Prenatal Development (3) Morphological, physiological, and biochemical phenomena in human embryonic and fetal development. Human birth defects and manipulation of gametes and embryos. Prerequisites: 01:119:101-102.

01:146:322Animal Histology (4) Structure of the tissues and organs of the animal body. (Formerly 01:119:322) Lec. 3 hrs., lab. 3 hrs. Prerequisite: 01:146:270.

01:146:327Parasitology (4) Cell biology, epidemiology, pathogenesis, and diagnosis of protozoan and metazoan parasites and arthropods of importance in medical, veterinary, and wildlife diseases. (Formerly 01:119:327) Lec. 3 hrs., lab. 3 hrs. Prerequisites: 01:119:101-102. Credit not given for both this course and 01:146:328

01:146:328Human Parasitology (3) Discussion of the cell biology, epidemiology, pathogenesis, and clinical manifestations of human parasitic diseases. (Formerly 01:119:328) Lec. 3 hrs. Prerequisites: 01:119:101,102. Credit not given for both this course and 01:146:327.

01:146:329Human Parasitology Laboratory (1) Laboratory to accompany 01:146:328. (Formerly 01:119:329) Lec. 3 hrs. Pre- or Corequisite: 01:146:328. Credit not given for both this course and 01:146:327.

01:146:356Systems Physiology (3) Comprehensive study of the principal organ systems of laboratory animals and man. (Formerly 01:119:356) Prerequisites: 01:119:101-102 and 01:160:161-162, 171

01:146:357Systems Physiology Laboratory (1) Laboratory to accompany 01:146:356. (Formerly 01:119:357) lab. 3 hrs. Pre- or Corequisite: 01:146:356.

01:146:405Honors Seminar (3) Development of communication and written skills needed by professionals in cell biology and neuroscience. Oral reports, written�papers, and discussion of topics of current interest in the field. Prerequisite: Permission of department. Open only to senior honors students.

01:146:406-407Research in Cell Biology and Neuro- science (1-4,1-4) Research under the direction of a member of the departmental faculty. Written report required. Prerequisite: Permission of instructor. Open only to students majoring in cell biology and neuroscience.

01:146:408-409Honors Research (3-6,3-6) Research project under the direction of a departmental faculty member. Written report and oral presentation required. Prerequisite: Permission of department. Open only to senior honors students.

01:146:445. Advanced Neurobiology I (4) Advanced concepts in neurobiology focusing on cellular and molecular aspects of neuronal signaling, including ion channel gating, sensory transduction, and transmission across chemical and electrical synapses. (Formerly 01:119:445) Prerequisite: 01:146:245.

01:146:446Advanced Neurobiology Laboratory I (3)

Advanced laboratory methods in neurobiology. Electrophysiological and immunochemical techniques to explore the structural and functional features of nerve cells.

(Formerly 01:119:448) Prerequisites: 01:146:445 and permission of instructor.

01:146:448Advanced Neurobiology Laboratory II (3)
Prerequisites: 01:146:447 and permission of instructor.

01:146:450Endocrinology (3) Endocrinology and neuroendocrinology of animals, including man. The structure and function of the endocrine glands, including the hypothalamus, and the biosynthesis and chemistry of hormones. (Formerly 01:119:450) Prerequisites: 01:119:101-102. Recommended: Courses in physiology and organic chemistry. Open to juniors and seniors only. Credit not given for both this course and 11:067:450.

01:146:464Topics in Cell Biology and Neuroscience (1-3) Directed readings and discussion of selected topics in cell biology and neuroscience. Prerequisites: 01:146:245 and 270.

01:146:470Advanced Cell Biology (3) Advanced concepts of cell biology focusing on the molecular organization of cells, including internal membranes and synthesis of macromolecules, the cell nucleus, the cell cycle, cytoskeleton, cell-cell adhesion and the extracellular matrix, and signal transduction. Prerequisite: 01:146:270. Credit not given for both this course and 01:119:370 or 378 or 01:146:370.

01:146:471Advanced Cell Biology Laboratory (3) Advanced laboratory methods in cell biology. Emphasis on light and electron microscopy, imaging, immunochemical techniques, tissue culture, and methods of identifying and separating macromolecules. Prerequisites: 01:146:470 and permission of instructor.

01:146:472Advanced Developmental Biology (3) Molecular biology of early development, morphogenesis, organogenesis, tissue interactions, and genetic control of cellular differentiation. Prerequisite: 01:146:270.

01:146:473Advanced Developmental Biology Laboratory (3) Advanced laboratory methods in developmental biology. Designed to introduce students to techniques of obtaining and handling gametes and experimental manipulation of embryos. Focus on sea urchin, frog, zebrafish, and chick. Prerequisites: 01:146:472 and permission of instructor.

01:146:474Immunology (3) Fundamental principles of immunology with emphasis on antibody�formation, immunoglobulin molecules and genes, hypersensitivity reactions, and the cellular basis for the immune response. (Formerly 01:119:474) Prerequisites: 01:119:101-102 and 01:447:380. Recommended: 01:447:390.

01:146:475Laboratory in Immunology (1) Biochemical and molecular analysis of immune cell function. Application of immunological techniques to the examination of normal and diseased states. Pre- or corequisite: 01:146:474.

01:146:478Molecular Biology (3) Structure and function of macromolecules, recombinant DNA technology, and study of genes and their regulation at the molecular and cellular levels. (Formerly 01:119:478) Prerequisites: 01:160:307-308. For juniors and seniors only.