16:118:405
Differential Equations in Biology (3)
Models for biological processes based on deterministic ordinary and partial differential equations. Topics include stability, bifurcations, periodic phenomena, transport, and diffusion.
Sontag. Prerequisites: Differential equations and linear algebra.
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16:118:503
Introduction to Computational Biology and Molecular Biophysics (3)
Introduction to the phenomena ranging from molecular interactions to biological behavior at the level of cells, tissues, and organisms.
Prerequisites: Linear algebra; calculus; and a good biology, chemistry, and physics background at the high school level.
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16:118:505
Mathematical Foundations for Biology (3)
This is a remedial course focusing on differential equations, Fourier and Laplace transforms, and stochastic processes for students interested in quantitative biology.
Prerequisites: Calculus, some undergraduate exposure to ODEs, linear algebra, and basic probability.
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16:118:507
Physics of Living Matter (3)
Review of physical phenomena that determine the properties of biological molecules, molecular assemblies, and fundamental biological processes. Also offered as 750:567.
Prerequisites: Linear algebra, differential equations, thermodynamics, and classical physics (at the junior level).
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16:118:511
Modeling of Biomolecular Networks: An Introduction to Systems Biology (3)
Focuses on a systems approach to biomolecular processes including the ideas, mathematical language, and modeling techniques used to describe the main mechanisms of transferring and processing of biological information.
Sengupta. Prerequisites: Differential equations, linear algebra, probability and statistics; good chemistry/biology background at the high school level.
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16:118:513
Molecular Simulations in Computational Biology (3)
Focuses on molecular modeling and simulations of biological macromolecules including proteins and nucleic acids, molecular dynamics and Monte Carlo methods, and solvation. Computer simulations and exercises are an integral part of the course. Also offered as 750:563.
Levy, Olson. Prerequisites: Advanced undergraduate courses in physical chemistry or physics.
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16:118:515
Statistical Methods in Bioinformatics (3)
Broadly applicable, modern statistical tools particularly important in modeling and interpreting noisy bioinformatics data.
Jornsten. Prerequisites: Linear algebra and calculus.
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16:118:601
Protein Physics (3)
Advanced introduction to protein folding, binding, and structure prediction including equilibrium and kinetic aspects of protein folding and binding, classification of protein folds, and structure prediction from sequence.
Levy. Prerequisite: Permission of instructor.
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16:118:613
Selected Math Topics in Physiology and Medicine (3)
Mathematical modeling of selected biological phenomena and systems. Cellular homeostasis, regulation of cell function, cardiac rhythmicity, and hormone physiology are potential topics.
Sontag. Prerequisite: Elementary differential equations or permission of instructor.
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16:118:616,617
Special Topics in Computational Biology and Molecular Biophysics (BA,BA)
Prerequisite: Permission of instructor.
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16:118:621,622
Laboratory Rotation in Computational Biology and Molecular Biophysics (1-2 BA,1-2 BA)
Introduction to the techniques of BioMaPS research through participation in research projects of selected members of the graduate faculty.
Enrollment restricted to Ph.D. students in the graduate program in computational biology and molecular biophysics. No more than a total of 3 credits of laboratory rotation can be earned.
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16:118:701,702
Research in Computational Biology and Molecular Biophysics (BA,BA)
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