The following courses have minimum prerequisites for undergraduate degrees in biochemistry, biology, chemistry, or microbiology with a concentration in genetics, organic chemistry, general biochemistry, or general microbiology.

16:681:530 (F) Molecular Medicine (3) Topics in human health and disease from a molecular biology perspective. Basic principles that promote an understanding of the human genome, gene regulation and expression, and genetic engineering will be applied to the diagnosis and treatment of human disease. Banerjee

16:681:535 (F) Human Genetics (3) Examination of molecular and chromosomal bases for human inherited diseases. Molecular approaches to gene identification, including position cloning and linkage analysis. Role of mutations, evaluation of repetitive sequences in the human genome. Brzustowicz. Prerequisite: Basic molecular genetics. Recommended: Biochemistry and physiology.

16:681:543 (S) Current Concepts of Immunology (3) Organization and evolution of the immune system, genetic basis of generation of diversity, MHC gene structure and function, development and selection of lymphocytes, lymphocyte activation, and the regulation of immune tolerance. Covey

16:681:555 (S) Molecular Virology (3) Molecular aspects of viral replication. Plant viruses, animal viruses, important causes of human disease. RNA and DNA viruses will be discussed. Lectures on viruses and tumorigenesis, viruses as vectors, host defenses against viral infection, the prevention of virus infections by vaccines, and antiviral chemotherapy. Roth

16:681:586 (S) Counseling Techniques for Genetic Counselors I (2) Instruction, delivery, and practice of psychosocial assessment and counseling skills in genetic counseling sessions. Techniques reinforced through structured role play and analysis of master videos. Joines et al.

16:681:587 (F) Counseling Techniques for Genetic Counselors II (2) Focuses on practice of psychosocial assessment and delivery of counseling skills during a genetic counseling session. Processing and analyzing cases from clinical rotations. Joines et al.

16:681:601 (S) Advanced Topics in Microbiology and Molecular Genetics: Grant-Writing Basics (1) Reviews basic grant-writing concepts and best practices, focusing on producing a clearly written specific aims page. Topics include funding agencies, types of grants, forms, budgets, proposal format, and the review process. Students will be required to write and critique a specific aims page on their research topic. This course may serve as a good start for students to begin writing for the research proposal that is required for their oral preliminary exam, which is required by most of the individual graduate programs in molecular biosciences at the end of their second year of study. Copeland

16:681:602 (F) Advanced Topics in Microbiology and Molecular Genetics: Molecular Oceanography (3) This course will highlight emerging efforts to elucidate the activity, diversity, and evolution of microbial genes and link them to key oceanic ecosystem and biogeochemical processes, by merging biochemistry, molecular biology, and genome-based approaches with innovative instrumentation. These efforts have begun to shed novel insight into staggering microbial biodiversity and a range of cellular strategies, including niche adaptation, stress response, cell communication, signaling, and defense, which strongly shape their ecological impact in the oceans. Bidle

16:681:603 (F) Advanced Topics in Microbiology and Molecular Genetics: Seminars in Microbiology (1) Informal critical description and discussion of current literature and concepts.
Haggblom

16:681:605 (F) Special Topics in Molecular Biology (1) A journal club course covering current literature in the field of RNA biology. Copeland. Prerequisites: Successful completion of MBS core curriculum and both qualifying exams.

16:681:606 (S) Teaching of Microbiology (2) Laboratory teaching experience with faculty direction and mentoring. Schein. Prerequisite: Permission of instructor.

16:681:607/608 Teaching Techniques in Microbiology and Molecular Genetics (2) Guidance and practical experience in the teaching of microbiology and molecular genetics. Prerequisite: Open only to matriculated students in the graduate program in microbiology and molecular genetics.

16:681:611,612,613,614 Laboratory Rotation in Microbiology and Molecular Genetics (2,2,2,2) Half-semester research projects of interest to the student in faculty laboratories. Prerequisite: Written approval of program director. Open only to matriculated students in the graduate program.

16:681:641,642 Independent Studies in Microbiology and Molecular Biology (BA,BA) Library research project normally leading to a nonthesis essay for master's degree candidates. Prerequisites: Permission of faculty adviser and program director.

16:681:643 (F) Advanced Topics in Immunology (3) Historic and current literature, problem solving, and data evaluation. Topics may include tolerance and autoimmunity, antigen presentation, transcriptional and epigenetic control of the immune system, B cell expansion, death and lymphoma development, macrophage activation, and cancer immunotherapy. Denzin et al. Prerequisites: 16:681:543 or similar. Undergraduate immunology and approval of instructor.

16:681:671 (F) Topics in the Translation of Research to Medicine (1) The interfaces between basic, translational, and clinical research. An introduction to the translational research problem and discussion of papers in the area of basic science that may become translational or clinical/translational papers. Millonig, Schein

16:681:681 (F) Seminar in Molecular Genetics and Microbial Physiology (1) Topics in molecular medicine. Discussion of journal articles focusing on recent advances in cancer research. The objectives of this course are to: 1) introduce students to molecular approaches used to understand, prevent, diagnose, or treat cancer; 2) develop skills to critically review scientific literature; and 3) develop effective scientific communication skill. Chaudhary

16:681:682 (S) Seminar in Human Genetics (2) Learning the recent advances in human genetics is an important step to take advantage of the exploding opportunities and build up a competitive career in biomedicine. The goal of this course is to provide an in-depth review of rapidly progressing and emerging knowledge, technologies, and resources in human genetics by reading, presenting, and discussing recently published literature of important topics. H. Li

16:681:683 Seminar in Virology, Immunology, and Pathogenic Microbiology: Yeast Genetics (1) The application of fungal systems to molecular and cellular biology--yeast genetics. Informal critical description and discussion of current literature and concepts. Vershon

16:681:685 Seminar on Chromatin and Gene Expression (1) Chromatin remodeling and gene regulation in eukaryotic organisms. Current literature in primary scientific journals. Each student will lead a group discussion once during the semester. The group is composed of students, postdoctoral associates, and faculty members. Belden

16:681:701,702 Research in Microbiology and Molecular Genetics (BA,BA)