The following courses have minimum prerequisites for undergraduate degrees in biochemistry, biology, chemistry, or microbiology with a concentration in genetics, organic chemistry, general biochemistry, or general microbiology.
(F) Molecular Medicine (3)
Topics in human health and disease from a molecular
biology perspective. Basic principles that promote an understanding of the
human genome, gene regulation and expression, and genetic engineering will be
applied to the diagnosis and treatment of human disease.
(F) Human Genetics (3)
Examination of molecular and chromosomal bases for human inherited
diseases. Molecular approaches to gene identification, including
position cloning and linkage analysis. Role of mutations, evaluation
of repetitive sequences in the human genome.
Brzustowicz. Prerequisite: Basic molecular genetics. Recommended: Biochemistry and physiology.
(S) Current Concepts of Immunology (3)
Organization and evolution of the immune system, genetic basis of generation of diversity, MHC gene structure and function, development and selection of lymphocytes, lymphocyte activation, and the regulation of immune tolerance.
(S) Molecular Virology (3)
Molecular aspects of viral replication. Plant
viruses, animal viruses, important causes of human disease. RNA and DNA viruses
will be discussed. Lectures on viruses and tumorigenesis, viruses as vectors,
host defenses against viral infection, the prevention of virus infections by
vaccines, and antiviral chemotherapy.
(S) Counseling Techniques for Genetic Counselors I (2)
Instruction, delivery, and practice of psychosocial
assessment and counseling skills in genetic counseling sessions. Techniques
reinforced through structured role play and analysis of master videos.
Joines et al.
(F) Counseling Techniques for Genetic Counselors II (2)
Focuses on practice of psychosocial assessment and delivery
of counseling skills during a genetic counseling session. Processing and
analyzing cases from clinical rotations.
Joines et al.
(S) Advanced Topics in Microbiology and Molecular Genetics: Grant-Writing Basics (1)
Reviews basic grant-writing
concepts and best practices, focusing on producing a clearly written specific
aims page. Topics include funding agencies, types of grants, forms, budgets,
proposal format, and the review process. Students will be required to write and
critique a specific aims page on their research topic. This course may serve as
a good start for students to begin writing for the research proposal that is
required for their oral preliminary exam, which is required by most of the
individual graduate programs in molecular biosciences at the end of their
second year of study.
(F) Advanced Topics in Microbiology and Molecular Genetics: Molecular Oceanography (3)
This course will
highlight emerging efforts to elucidate the activity, diversity, and evolution
of microbial genes and link them to key oceanic ecosystem and biogeochemical
processes, by merging biochemistry, molecular biology, and genome-based
approaches with innovative instrumentation. These efforts have begun to shed
novel insight into staggering microbial biodiversity and a range of cellular
strategies, including niche adaptation, stress response, cell communication,
signaling, and defense, which strongly shape their ecological impact in the
(F) Advanced Topics in Microbiology and Molecular Genetics: Seminars in Microbiology (1)
Informal critical description and discussion of current literature and concepts.
(F) Special Topics in Molecular Biology (1)
A journal club course covering current literature in the field of RNA biology.
Copeland. Prerequisites: Successful completion of MBS core curriculum and both qualifying exams.
(S) Teaching of Microbiology (2)
Laboratory teaching experience with faculty direction and mentoring.
Schein. Prerequisite: Permission of instructor.
Teaching Techniques in Microbiology and Molecular Genetics (2)
Guidance and practical experience in the teaching of microbiology and molecular genetics.
Prerequisite: Open only to matriculated students in the graduate program in microbiology and molecular genetics.
Laboratory Rotation in Microbiology and Molecular Genetics (2,2,2,2)
Half-semester research projects of interest to the student in faculty laboratories.
Prerequisite: Written approval of program director. Open only to matriculated students in the graduate program.
Independent Studies in Microbiology and Molecular Biology (BA,BA)
Library research project normally leading to a nonthesis essay for master's degree candidates.
Prerequisites: Permission of faculty adviser and program director.
(F) Advanced Topics in Immunology (3)
Historic and current literature, problem solving, and data
evaluation. Topics may include tolerance and autoimmunity, antigen
presentation, transcriptional and epigenetic control of the immune
system, B cell expansion, death and lymphoma development, macrophage
activation, and cancer immunotherapy.
Denzin et al. Prerequisites: 16:681:543 or similar. Undergraduate immunology and approval of instructor.
(F) Topics in the Translation of Research to Medicine (1)
The interfaces between basic, translational, and clinical research. An introduction to the translational research problem and discussion
of papers in the area of basic science that may become translational or clinical/translational papers.
(F) Seminar in Molecular Genetics and Microbial Physiology (1)
Topics in molecular medicine. Discussion of journal articles focusing on recent advances
in cancer research. The objectives of this course are to: 1) introduce students to
molecular approaches used to understand, prevent, diagnose, or treat cancer; 2)
develop skills to critically review scientific literature; and 3) develop
effective scientific communication skill.
(S) Seminar in Human Genetics (2)
Learning the recent advances in human genetics is an
important step to take advantage of the exploding opportunities and build up a
competitive career in biomedicine. The goal of this course is to provide an in-depth review of rapidly progressing and emerging knowledge, technologies, and
resources in human genetics by reading, presenting, and discussing recently
published literature of important topics.
Seminar in Virology, Immunology, and Pathogenic Microbiology: Yeast Genetics (1)
The application of fungal systems to molecular and cellular biology--yeast genetics. Informal critical description and discussion of current literature and concepts.
Seminar on Chromatin and Gene Expression (1)
remodeling and gene regulation in eukaryotic organisms. Current
literature in primary scientific journals. Each
student will lead a group discussion once during the semester. The
group is composed of students, postdoctoral associates, and
Research in Microbiology and Molecular Genetics (BA,BA)