50:160:101 Consumer Chemistry (R) (3) * Introduces areas of chemistry that are encountered in everyday living. Typical topics include nuclear chemistry, power plants, nuclear waste, radiation therapy, food chemistry, additives, fats, carbohydrates, proteins, fermentation, consumer products, soaps, toothpaste, detergents, drugs, and pharmaceuticals from aspirin to vitamins. For nonscience majors.

50:160:105 Development of Modern Chemistry (R) (3) * A broad descriptive view of the development of modern chemistry from the classical Greek arts to the chemical sciences of the 21st century. For nonscience majors.

50:160:107-108 General Chemistry I,II (R) (3,3) * First term: introduction to the scope and method of chemistry, concepts of atomic and molecular structure, major theories of chemical change, and the development of fundamental laws governing chemical reactions. Second term: largely devoted to an introduction to organic chemistry, with particular emphasis on biologically active compounds. Lec. 3 hrs. Primarily for students majoring in nursing and other allied health professions. Corequisite for 50:160:107: 50:160:109. Corequisite for 50:160:108: 50:160:110.

50:160:109-110 General Chemistry Laboratory I,II (R) (1,1) * Laboratory exercises to demonstrate the fundamental principles of chemistry. Laboratory fee: $40. Rec. 1 hr., lab. 2 hrs. Pre- or corequisite for 50:160:109: 50:160:107. Pre- or corequisite for 50:160:110: 50:160:108.

50:160:115-116 Chemical Principles I,II (R) (3,3) * Introduction to fundamental principles of chemistry; atomic structure; bond characteristics of gases, liquids, solids, and solutions; acids and bases; rates of chemical reactions; and chemical equilibria. Study of common elements and their compounds. Pre- or corequisite for 50:160:115: 50:160:125. Prerequisites for 50:160:116: 50:160:115 and 125. Pre- or corequisites for 50:160:116: 50:160:126, and either 50:640:121 or 130. 50:160:116 is a prerequisite for all advanced chemistry courses. Primarily for students planning to major in the natural sciences or engineering.

50:160:125-126 Chemical Principles Laboratory I,II (R) (1,1) * Demonstrates fundamental chemical principles and chemical properties of matter. Laboratory fee: $40. Rec. 1 hr., lab. 2 hrs. Pre- or corequisite for 50:160:125: 50:160:115. Prerequisites for 50:160:126: 50:160:115 and 125. Pre- or corequisite for 50:160:126: 50:160:116. 50:160:126 is a prerequisite for all advanced chemistry courses.

50:160:201 Environmental Chemistry (3) * Natural and human-made chemical compositions and chemical changes of the hydrosphere, the lithosphere, and the atmosphere and how they lead to the preservation and enhancement of life on earth. Prerequisite: 50:160:116 or permission of instructor.

50:160:325 Analytical Chemistry (4) Introduction to the principles and practice of gravimetric, volumetric, spectrometric, and electroanalytical methods of measurement and precipitation, extraction, and chromatographic methods of separation. Laboratory fee: $40. Lec. 3 hrs., lab. 3 hrs. Prerequisites: 50:160:116 and 126. Corequisite: 50:160:329.

50:160:326 Instrumental Analysis (4) Principles and practice of qualitative analysis in the chemical sciences using modern instrumental methods, including electrochemistry; gas and high-performance liquid chromatography; and ultraviolet, infrared, nuclear magnetic resonance, and mass spectrometry. Laboratory fee: $40. Lec. 3 hrs., lab. 3 hrs. Prerequisites: 50:160:336, 340. Corequisite: 50:160:330.

50:160:335-336 Organic Chemistry I,II (3,3) 50:160:335: Introduction, structure and properties, stereochemistry, alkyl halides, nucleophilic substitution and elimination, alkenes, alkynes, alcohols, NMR, IR, MS. 50:160:336: Ethers and epoxides, conjugated systems, MO theory, aromatic compounds, electrophilic aromatic substitution, aldehydes and ketones, amines, carboxylic acids, carboxylic acid derivatives. Lec. 3 hrs., rec. 1 hr. Prerequisites for 50:160:335: 50:160:116, 126. Pre- or corequisite for 50:160:335: 50:160:339. Prerequisites for 50:160:336: 50:160:335, 339. Pre- or corequisite for 50:160:336: 50:160:340. Both courses must be completed to receive credit.

50:160:339-340 Organic Chemistry Laboratory I,II (1,1) 50:160:339: Introduction to the techniques used in the synthesis, isolation, and identification of organic compounds; stereochemistry. 50:160:340: Multistep synthesis; isolation, identification, and synthesis of natural products; instrumentation techniques. Laboratory fee: $40. Lab. 3 hrs., rec. 1 hr. Prerequisites for 50:160:339: 50:160:116, 126. Pre- or corequisite for 50:160:339: 50:160:335. Prerequisites for 50:160:340: 50:160:335, 339. Pre- or corequisite for 50: 160:340: 50:160:336.

50:160:343 Structure and Bonding (3) Introduction to the concepts of quantum chemistry as applied to the energetics and spectroscopy of the chemical bond; laboratory emphasizes the use of the latest graphics workstations in molecular modeling. Prerequisites: 50:160:336 and 340.

50:160:345-346 Physical Chemistry (3,3) Thermodynamics with chemical applications, kinetics, quantum mechanics, statistical mechanics, transport, and structure. Chemistry prerequisite: 50:160:116, 126. Math pre- or corequisites: 50:640:221, and 50:640:250 or 314. Physics prerequisites: 50:750:131-132, 133-134 or 50:750:203-204, 205, 206. Note that 50:160:345 is a prerequisite for all 400-level courses in chemistry.

50:160:347-348 Physical Chemistry Laboratory (1,1) Laboratory experiments that illustrate physical chemistry principles, including research-level equipment and simulations on state-of-the-art workstation. Pre- or corequisite for 50:160:347: 50:160:345. Pre- or corequisite for 50:160:348: 50:160:346.

50:160:396 Honors Program in Chemistry (4) See Departmental Honors Programs in the Degree Requirements chapter.

50:160:412 Inorganic Chemistry Laboratory (1) Preparation and structural determination of inorganic compounds using a variety of techniques. Laboratory fee: $40. Lab. 3 hrs. Prerequisite: 50:160:413. Pre- or corequisite: 50:160:414.

50:160:413 Inorganic Chemistry I (3) The fundamentals of inorganic chemistry including atomic and molecular structure bonding, modern concepts of acids and bases, solvent systems, redox, and coordination chemistry set against a background of the periodic system. Prerequisite: 50:160:345.

50:160:414 Inorganic Chemistry II (3) Selected topics of inorganic chemistry, such as chemistry of the transition metal complexes and main group elements (structural, bonding, electronic, and magnetic properties; kinetics, reaction mechanisms, and spectroscopy), organometallic, bioinorganic, or materials chemistry. Prerequisite: 50:160:413.

50:160:415 Radioisotope Methodology (4) Introduction to the fundamental principles of radiation; its detection and measurement; and its application in chemistry, biology, and the medical sciences. Lec. 3 hrs., lab. 3 hrs. Prerequisite: 50:160:336 or permission of instructor. Offered in alternate years.

50:160:435 Advanced Organic Chemistry I (3) Devoted largely to the structure and properties of organic molecules and their reactions. Reaction mechanisms emphasized. Prerequisites: 50:160:336, 345; 50:640:122 or 130.

50:160:436 Advanced Organic Chemistry II (3) Devoted largely to organic synthesis. Mechanisms stressed. Prerequisite: 50:160:435 or permission of instructor.

50:160:437 Solid-State Chemistry (3) Experimental and theoretical aspects of solids. Topics include synthetic and crystal growth methods; crystal structures; structural characterizations; phase diagrams; chemical, physical and electronic properties of solids. Prerequisite: 50:160:345 or permission of instructor.

50:160:438 Solid-State Chemistry Laboratory (1) Experimental methods and techniques for the preparation of solid-state materials. Use of X-ray, optical, and thermal instruments for structural analysis and property studies. Prerequisite: Permission of instructor.

50:160:440 Kinetics (2) The classification and interpretation of chemical reactions through study of their kinetic behavior. Lec. 2 hrs. Prerequisite: 50:160:443.

50:160:441 Advanced Organic Chemistry Laboratory I (2) The structure of organic compounds determined using spectrophotometric analytical techniques and calculated with molecular modeling programs. Breakage deposit: $25. Lec. 1 hr., lab. 3 hrs. Corequisite: 50:160:435.

50:160:442 Advanced Organic Chemistry Laboratory II (1) Organic compounds synthesized using advanced techniques from the literature. Breakage deposit: $25. Lab. 3 hrs. Prerequisites: 50:160:435 and permission of instructor.

50:160:443 Thermodynamics (3) The principles of thermodynamics and their application to the study of homogeneous and heterogeneous equilibria. Prerequisite: 50:160:346.

50:160:444 Polymer Chemistry (3) Topics include synthesis, characterization, and thermodynamics of conventional organic and inorganic polymers as well as conducting polymers and biopolymers. Prerequisites: 50:160:345, 435, or permission of instructor.

50:160:446 Polymer Chemistry Laboratory (1) Synthesis and characterization of polymers to illustrate principles of polymer science. Prerequisite: Permission of instructor.

50:160:447 Computational Chemistry (3) Application of numerical and graphical techniques to data acquisition and presentation in chemistry, including molecular modeling and microprocessor control in spectroscopy. Prerequisites: 50:160:326, 336; 50&64:198:111; and 50&64:640:221; or permission of instructor.

50:160:448 Quantum Chemistry and Pharmacology (4) Topics include molecular orbital theory and electron correlation methods that are applied to the study of states and configuration in spectroscopy, and reaction mechanisms. Calculation of the properties of polymers and molecules of organic and pharmacological interest. The laboratory introduces computer programs in parallel with the chemical theory. Lec. 3 hrs., lab. 3 hrs. Prerequisites: 50:160:346 and permission of instructor.

50:160:451,452 Electroactive Materials I,II (BA,BA) Preparation (both chemical and electrochemical) of materials on electrode surfaces; structural and spectroscopic analysis of the materials. Prerequisite: Permission of instructor.

50:160:453,454 Synthesis and Characterization of Conducting Polymers I,II (BA,BA) Preparation and analysis of conducting polymers. Characterization techniques such as 4-probe conductivity and spectroscopic analysis emphasized. Prerequisite: Permission of instructor.

50:160:455,456 Quantum Computational Laboratory I,II (BA,BA) Introduction to advanced quantum mechanics. Numerical methods in quantum chemistry. Original research. Prerequisite: Permission of instructor.

50:160:457,458 Density-Functional Thermochemistry I,II (BA,BA) Introduction to density-functional theory; calculation techniques; development of functionals. Original research. Prerequisite: Permission of instructor.

50:160:459,460 Molecular Modeling I,II (BA,BA) Methods for the calculation and display of chemical and physical properties explored through the use of supercomputers and high-end graphics workstations. Prerequisite: Permission of instructor.

50:160:461,462 Reaction Mechanisms I,II (BA,BA) Theoretical calculations using molecular orbital, electron correlation, and density functional theories performed and studied in relation to experimental quantities. Prerequisite: Permission of instructor.

50:160:463,464 Research in Bioinorganic Chemistry I,II (BA,BA) Identification and quantification of biologically active forms of metals by spectrometry and chromatography from both nutritional and toxicological perspectives. Prerequisite: Permission of instructor.

50:160:465,466 Research in Radiochemistry and Radiation Chemistry I,II (BA,BA) Characterization of recoil reactions associated with ⁵⁰Cr nuclei in hexavalent chromium compounds and/or ⁵⁵Mn nuclei in heptavalent manganese compounds undergoing specific processes. Prerequisite: Permission of instructor.

50:160:467,468 Crystalline Structures and Synthesis I,II (BA,BA) Introduction to a variety of synthetic routes for the crystal growth of novel inorganic materials, such as carbides, pnictides, oxides, and chalcogenides. Prerequisite: Permission of instructor.

50:160:469,470 Preparation and Characterization of Inorganic Materials I,II (BA,BA) Application of low and high temperature techniques for preparation, purification, and identification of inorganic compounds with molecular, chain, layered, and extended three-dimensional structures. Investigation of their structural, electronic, optical, and thermal properties. Prerequisite: Permission of instructor.

50:160:471,472 Research in Analytical Chemistry I,II (BA,BA) Topics include applications of atomic spectrometry and voltammetric techniques to the speciation of trace elements in environmental and biological systems; the development of isolation procedures for microcomponents of environmental and biological systems; the development of biomarkers for retrospective assessments of dose and the development of biosensors for pollutants and contaminants. Prerequisite: Permission of instructor.

50:160:491,492 Chemistry Seminar (1,1) Members of the seminar prepare and present papers on topics of current interest in chemistry. Sem. 1 hr. Prerequisite: Permission of instructor.

50:160:493,494 Special Topics in Chemistry (BA,BA) The subject matter varies according to the interests of the instructor and is drawn from areas of current chemical interest. Prerequisite: Permission of instructor.

50:160:495,496 Research in Chemistry (BA,BA) For the student interested in cooperating in research with a member of the faculty. The student should work out a research project with the instructor before registering for the course. Prerequisites: 50:160:325, 326, and senior status or permission of instructor. Maximum of 4 credits may be earned toward the chemistry major in 495 and 496 combined.

50:160:497,498 Honors Program in Chemistry (4,4) See Departmental Honors Programs in the Degree Requirements chapter.