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11:126:111
Ethical and Scientific Challenges in Biotechnology (3)
Applications and implications of biotechnology, including ethical and social controversies. Two 80-minute lecture periods, a large portion of which is discussion and student presentations and includes invited expert speakers.
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11:126:296
Honors Seminar (3)
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11:126:383
Nucleotide Sequence Analysis (3)
Introduction
to DNA, RNA, and amino acid sequence analysis using publically available and
web-based tools such as Blast, Clustal, etc. and biological databases such as NCBI,
Genbank, and OMIM. Exercises in genetic
manipulation, recombinant DNA technology, and restriction mapping using programs
like NEBcutter, Net Primer, and Primer 3Plus.
Prerequisites: 01:160:308 and 01:447:380. Offered spring and fall semesters.
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11:126:401
Seminar in Biotechnology (1.5)
Development of communication skills needed by professionals in the field of biotechnology through student oral presentations and facilitated discussion. Topics include current scientific advances in biotechnology and the social impact of biotechnology.
One 80-min. lec. Open only to seniors majoring in biotechnology.
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11:126:407
Comparative Virology (3)
Biology of viruses and approaches to control through antivirals and genetic engineering. Genome organization, gene expression, replication, movement, and transmission across kingdoms.
Prerequisites: 01:119:115-116,117 (formerly 01:119:101-102), 01:160:308. Offered in odd-numbered years in the fall semester.
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11:126:410
Process Biotechnology (3)
Survey of the applications of biotechnology, emphasizing the pharmaceutical industry and the operation of fermentation systems. Case studies of downstream separation and purification protocols employed on an industrial scale.
Prerequisites: 11:680:390, one semester of 11:115:403 or 01:694:407. Offered in odd-numbered years in the spring semester.
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11:126:413
Plant Molecular Biology (3)
Fundamental and applied aspects of plant molecular biology: structure, expression, and isolation of plant nuclear genes; molecular biology of plant development, plant organelles, and plant-microbe interactions; and plant biotechnology.
Prerequisites: 01:447:380 and 11:126:481 or 11:115:404 or 01:694:408. Offered in even-numbered years in the spring semester.
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11:126:427
Methods and Applications in Molecular Biology (4)
Introduction to techniques and experimental approaches used in eukaryotic molecular biology.
One 80-min. lec., one 80-min. rec., one 280-min. lab. Prerequisites: 01:447:380 and completion of 11:126:481 and 482 with grades of C or better. Offered fall semesters.
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11:126:434
Molecular Delivery Applications in Biotechnology (3)
Applications
and mechanisms-of-action of formulated and natural biological delivery systems--liposomes, carbon-based nanostructures, polymeric complexes, dendrimers, viruses,
extracellular vesicles, etc. A broad range of applications from agricultural
to pharmaceutical.
Two 80-min. lec., including class discussion and presentations. Prerequisites: 01:160:308 and 11:680:390; 11:115:403 or 01:694:407 highly recommended. Offered spring semesters.
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11:126:444
Advanced Technologies in Biosciences (3)
Lecture
and demonstration of advanced instrumentation and other advanced technologies
in bioscience. Includes demonstration of
each instrument, detailed description of data analysis and interpretation of
results. Methods include confocal
microscopy, surface plasmon resonance detection, quantitative PCR, mass
spectroscopy, flow cytometry/cell sorting, genotyping, TNO intestinal models.
Two 80-min. periods of lectures and demonstrations. Prerequisite: 11:115:403 or 01:694:407 or 11:126:481. Offered spring semesters.
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11:126:481
Molecular Genetics (3)
Principles of genetics at the molecular level, including the chemical nature of hereditary material. The genetic code, regulatory mechanisms, the molecular basis of mutation, DNA replication and recombination.
Prerequisites: Organic chemistry and completion of 01:447:380 with a grade of C or better. Offered fall semesters.
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11:126:482
Molecular Genetics Laboratory (4)
Biochemical and molecular aspects of gene function and gene recombination.
One 280-min. lab., one 80-min. lab., one 80-min. lec. Prerequisites: Completion of 11:126:481 with grade of C or better and 11:680:390. Offered spring semesters.
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11:126:484
Bioinformatics (3)
The
course introduces: (a) various biological metadatabases such as
NCBI, Ensembl, UCSC-Genome browser, TAIR, etc.; (b) methods of DNA sequencing and
sequence analysis; (c) methods of RNA expression analysis; (d) protein families and domains;
(e) protein structure prediction and three-dimensional structure
of proteins; (f) significance of mutations, single nucleotide polymorphisms, and
biomarkers in disease characterization; (g) tools used in structural bioinformatics; and (h) in silico drug
design and discovery.
Prerequisite: 01:126:481 or 11:126:383.
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11:126:486
Functional Genomics for Research (3)
Focuses on execution of tools and protocols used to elucidate the biology, ecology, and life histories of organisms through analysis of their genomes using algal genomes as models.
Prerequisites: One semester biology (01:119:115 or equivalent) and (11:216:251/486 or 01:447:380 or 11:115:301/403 or 01:694:315/407).
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11:126:497,498
Research in Biotechnology (BA,BA)
Independent research projects in biotechnology under the guidance of a faculty member.
Prerequisites: Permission of undergraduate program director and faculty adviser.
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