Pharmacology and Toxicology 718

30:718:304 Pathophysiology (3) General principles of disease and their application to the study of clinical disorders that affect the body as a whole, its specific systems, and individual organs. Lec. 3 hrs. Practicum provided as needed. Prerequisite: 01:119:102. Corequisite: 01:694:301.

30:718:320 Introduction to Pharmacology (3) Chemical structure, physiochemical properties, drug absorption, and metabolism of medicinal agents. Prerequisite: 01:694:301.

30:718:401 Theoretical Aspects of Pharmacology (2) Introduction to some of the emerging theoretical concepts and principles in the areas of biochemistry, molecular biology, cell biology, physiology, and human genomics. Theoretical concepts and principles surveyed applied to pharmacologically relevant topics, such as receptor-ligand interactions, signal transduction, genotype-phenotype coupling, and others. Prerequisite: First professional year standing or higher.

30:718:405-406 Pharmacology I,II (3,3) Effects of drugs on living systems, the mechanism of their effects, and their application to the therapy of disease. Prerequisite: 30:718:304.

30:718:409 Pharmacogenomics (2) Survey of the polymorphisms (population and individual differences) in the pharmacokinetics and pharmacodynamics of therapeutic drugs. Genetics and molecular basis of these polymorphisms and examples of associated abnormal responses to therapeutic agents and sensitivity to environmental toxicants. Prerequisites: One year of pharmacology or graduate standing and consent of instructor.

30:718:495,496,497,498 Research in Pharmacology (BA) Undergraduate research in pharmacology. Prerequisite: Permission of instructor. No more than two research courses may be used to satisfy degree requirements.