16:115:556Ethical Scientific Conduct (1) |
16:663:501Medicinal Chemistry Research Techniques and Principles (3) For students preparing to do research in medicinal chemistry. Topics include information management, computer methods, basic laboratory techniques, bioassey techniques, metabolism, pro-drugs, and quantitative structure-activity relationships. Kimball, Rice, Weyand |
16:663:502Principles of Drug Design (3) Principles of drug design. Topics include identifying new drug leads, drug absorption and distribution, pharmacomodulation, enzymes and receptors as targets, peptidomimetics, computer-aided drug design, and combinatorial chemistry. Hu, Kerrigan |
16:663:504Strategies and Tactics in Synthetic Medicinal Chemistry (3) Strategies and tactics for the design of syntheses for organic pharmaceutical agents; strategies for the preparation of series of analogs for structure-activity investigations. Kimball, Rice. Prerequisite: 16:160:503. |
16:663:505Drugs: Structure and Function (3) Survey of the major pharmaceutical agents in clinical use. Emphasis on the influence of chemical structure in the elicitation of pharmacological effects. LaVoie, Rice, Weyand. Prerequisites: 01:160:305,306 or equivalent. |
16:720:507Advanced Pharmaceutics I (3) Application of physical-chemical principles to the study and evaluation of pharmaceutical systems: solubility phenomena, equilibria, complexation, phase transitions, and pharmaceutical stability, and the fundamentals of pharmacokinetics. Sinko. Prerequisites: Physical chemistry and associated math requirements. |
16:720:509Advanced Pharmaceutics II (3) Kinetics aspects of the pharmaceutical sciences. Quantitative and mechanistic approaches to pharmacokinetics, dissolution rate, and chemical kinetics. Kong. Prerequisites: Ordinary differential equations (or equivalent) and pharmacokinetics. |
16:720:510Advanced Pharmacokinetics (3) Kinetics of drug absorption, distribution, and elimination; clearance concepts; compartmental, noncompartmental, and physiological models. Sinko. Prerequisites: 01:160:327,328. |
16:720:520Therapeutic Peptides and Delivery Systems (3) Study of biochemical, biopharmaceutical, and pharmacologic bases of peptide- and protein-based macromolecular drugs, and application of multidisciplinary approaches to their formulation, development, and systemic delivery. Knipp. Prerequisites: 01 or 11:115:301; 30:721: 301,302, 403,404, or permission of instructor. |
16:720:522Controlled Drug Delivery Release (3) Multidisciplinary approaches to concepts, fundamentals, and biomedical assessments in the research and development of novel drug delivery systems. Cook. Prerequisites: 16:720:507, 515,516. |
16:720:540Independent Research Proposal (3) Develop a written research proposal using the standard HHS/ NIH format as part of the Ph.D. degree requirements. Proposal is evaluated as to its originality, scientific merit, and quality. Enrollment limited to Ph.D. candidates with approval of their adviser. |
16:720:601,602Seminar in Pharmaceutical Science (1,1) Presentation and discussion of recent developments in the pharmaceutical sciences. |
16:720:607,608Special Topics (3,3) Selected topics in pharmaceutical science. |
16:720:609Molecular and Functional Genomic Aspects of Membrane Transport (3) You |
16:720:610,611Independent Study in Pharmaceutical Science (BA,BA) Independent library and/or laboratory research into special aspects of pharmaceutical science; arranged under the supervision of a specific faculty member. No more than 3 credits may be taken as part of a student`s program. |
16:720:612,613Current Topics in Pharmaceutical Science (1,1) Seminar with lectures by scientists from the pharmaceutical industry on advanced topics within a particular area of pharmaceutical science, such as medicinal chemistry, pharmaceutical analysis, and pharmaceutics. |
16:720:701,702Research in Pharmaceutical Science (BA,BA) |
16:960:590Design of Experiments (3) |