26:160:503
Modern Synthetic Organic Chemistry (3)
Survey of selected preparative methods used in modern organic chemistry, with attention to the mechanisms by which they operate, their stereochemical characteristics, and their application to the synthesis of complex molecules.
Prerequisite: Advanced organic chemistry.
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26:160:511
Advanced Organic Chemistry (3)
Advanced survey of organic chemistry topics: carbanions, organometallic reagents and their application to C-C bond formation, radicals, photochemical reactions, protective groups, and examples of multistep syntheses.
Prerequisite: Elementary organic chemistry course.
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26:160:512
Special Topics in Organic Chemistry (3)
Advanced topics of current interest.
Prerequisite: Undergraduate degree in chemistry.
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26:160:514
Polymer Chemistry (3)
Introduction to the chemistry and materials properties of high polymers. Topics include polymerization techniques, properties of high polymers, principles of polymer characterization, conducting polymers, inorganic polymers, and biological polymers.
Prerequisite: Undergraduate degree in chemistry.
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26:160:515
Chemical Structure Determination (3)
Physical methods, mechanistic origins, and interpretation of infrared, ultraviolet, mass, 1H nuclear magnetic resonance, and 13 C NMR spectra, concentrating on deduction of organic structures. Some discussion of X-ray structure determination included.
Prerequisite: Undergraduate degree in chemistry.
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26:160:517
Photochemistry (3)
Contemporary issues in photochemistry, selected research from classical organic photochemistry and charge and electron transfer in donor-spacer-acceptor systems, charge transfer on the nanoscale, with reference to materials and biologicals.
Prerequisites: Undergraduate organic and physical chemistry.
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26:160:519
Physical Organic Chemistry (3)
Physical basis underlying principles of structure and reactivity in organic chemistry. Emphasis placed on determination of reaction mechanisms and on computational approaches to questions about organic molecules. Includes an introduction to the use of modern electronic-structure calculations.
Prerequisites: One year each of organic and physical chemistry.
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26:160:520
Advanced Mathematics for Chemists (3)
Review of infinite series, introduction to differential equations, matrix algebra, and group theory, and special functions as applied to chemistry.
Prerequisites: Elementary courses in calculus and physical chemistry.
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26:160:529
Special Topics in Physical Chemistry (3)
Advanced topics of current interest.
Prerequisite: One year of physical chemistry.
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26:160:532
Molecular Quantum Mechanics (3)
Basic principles and methods of quantum mechanics, with emphasis on their application to atoms and molecules.
Prerequisite: Physical chemistry.
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26:160:534
Thermodynamics and Kinetics (3)
Topics include mathematical methods; thermodynamic laws; free energy, enthalpy, and entropy; equilibria; standard and reference states; theories of chemical reaction rates; kinetics of simple and complex systems; experimental techniques and methods of mechanistic investigation.
Prerequisite: Physical chemistry.
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26:160:535
Crystal and Molecular Structure (3)
Symmetry of crystals: point groups, space lattices, and space groups. Determination of crystal structure by X-ray diffraction, including modern techniques; neutron diffraction, and other methods for determining molecular structure.
Prerequisite: Elementary physical chemistry.
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26:160:540
Principles of Spectroscopy (3)
Provides the general theoretical groundwork necessary for understanding the interaction between electromagnetic radiation (light) and matter (molecules, solids, nanoparticles). Practical illustrations are drawn from electronic and vibrational spectroscopy, however, the primary goal is to provide a broad basis applicable to any type of spectroscopy, from routine UV-vis absorption to multidimensional NMR. After a brief review of quantum mechanics the course proceeds to the concepts of transition probability, absorption, emission, dispersion, stimulated emission and laser action. Scientific graphing and analysis software is used extensively in order to allow students to explore the response of equations to physically important variables and parameters. In this fashion, by combining traditional solutions with visualization, a deeper and more intuitive understanding of the underlying physics is achieved.
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26:160:544
NMR Spectroscopy: Principles and Applications (3)
The course is intended to serve a broad audience seeking a background in principles behind the methodology. Topics covered include instrumentation, classical concepts, data collection, analysis, and spectral interpretation.
Prerequisite: Undergraduate degree in chemistry.
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26:160:545
Scanning Probe Microscopy (3)
Introduction to scanning probe microscopy and applications. Topics include principles of the scanning probe microscope family; instrumentation; and applications in chemistry, biology, and the semiconductor industry. Special emphasis paid to nanoscience and nanotechnology.
Prerequisite: Undergraduate degree in science or engineering.
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26:160:547
Analytical Spectroscopy (3)
Theoretical principles of spectroscopy: emission, infrared, Raman fluorescence, 1D and 2D multinuclear NMR, X-ray, and Fourier transformation techniques. Applications illustrating the various methods chosen from physical and organic chemistry.
Prerequisites: Elementary courses in analytical, organic, and physical chemistry.
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26:160:548
Special Topics in Analytical Chemistry (3)
Advanced topics of current interest.
Prerequisite: Elementary analytical chemistry.
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26:160:549
Electroanalytical Chemistry (3)
Application of electrochemical principles, with emphasis on analytical areas. Topics include selective-ion electrodes, pulse polarography, cyclic voltammetry, and coulometry.
Prerequisites: Analytical chemistry and a physical chemistry laboratory.
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26:160:571
Inorganic Chemistry (3)
Discussion of the structure (including symmetry) and reactivity (including mechanism) of both main-group and transition-metal compounds, and an introduction to transition-metal organometallic chemistry.
Prerequisites: Elementary courses in organic, inorganic, and physical chemistry.
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26:160:575
Organometallic Chemistry (3)
Introduction to the chemistry of transition-metal organometallic compounds. Includes an overview of ligand types, reactions, synthesis, and characterization of organometallics. Applications to catalysis, organic synthesis, and materials chemistry are discussed.
Prerequisites: Undergraduate inorganic and organic chemistry.
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26:160:576
Transition Metal-Based Homogeneous Catalysis (3)
Transition metal-based molecular catalysts are invaluable tools in both small molecule and polymer synthesis and are used extensively in the pharmaceutical, cosmetic, textile, and food industries. Begins with a brief overview or organometallic chemistry and catalysis. Subsequent modules on small molecule and polymer synthesis are then presented. Topics of current interest are emphasized.
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26:160:577
Main Group Metal Chemistry (3)
Covers the basic concepts as well as recent advances and developments in main group metal chemistry. Special emphasis is placed on the synthesis, properties, and reactivity of main group organometallic compounds.
Several topics of intense current interest are discussed in more detail: the development of multifunctional Lewis acids, the stabilization of low-valent metal complexes, the realization of multiple bonding for the heavier elements, the synthesis of organometallic polymers and luminescent materials, and the application of main group organometallic species in homogeneous catalysis.
Prerequistes: Undergraduate inorganic and organic chemistry.
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26:160:579
Special Topics in Inorganic Chemistry (3)
Advanced topics of current interest.
Prerequisite: 26:160:571 or equivalent.
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26:160:581
Biochemistry I (3)
Examination of the structures, properties, and functions of proteins, lipids, nucleic acids, and carbohydrates used by biological systems; quantitative application of kinetic and thermodynamic principles to understanding biological interactions, structures, and functions. Metabolism of lipids, carbohydrates, and amino acids.
Recommended: Introductory courses in physical chemistry and biology.
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26:160:583
Cellular and Molecular Biophysics I (4)
Introduction to current methodologies for determining biomolecular structure and dynamics. Topics include use of NMR and of IR, UV-visible, and fluorescence spectroscopies with conventional and laser light sources for studying the structure and dynamics of proteins, membranes, and nucleic acids, as well as steady-state and presteady-state enzyme kinetics.
Prerequisites: One year of elementary organic chemistry, physical chemistry, and biology; permission of instructor.
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26:160:584
Enzyme Kinetics and Mechanism (3)
Examination of methods, primarily kinetic, used to study the mechanisms of enzyme-catalyzed reactions. Illustrative examples taken from the biochemical literature.
Prerequisites: Organic chemistry, introductory physical chemistry, and biochemistry.
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26:160:585
Physical Biochemistry (3)
Principles of physical chemistry as applied to the study of macromolecules of biochemical importance; physical principles relating to the structure and function of proteins; hydrodynamic, spectroscopic, and chemical methods in the study of the structure and function of biomolecules.
Recommended: Biochemistry.
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26:160:586
Analytical Biochemistry (3)
Discussion of current methodology in the analysis of biologically important molecules; HPLC of amino acids, peptides, proteins, and nucleic acids; sequencing of proteins and nucleic acids; microchemical techniques to detect ultramicroscale quantities of biologically relevant substances.
Prerequisite: Elementary course in analytical chemistry.
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26:160:587
Topics in Biochemistry (3)
Metabolic pathways via their organic chemical reactions and reaction mechanisms. Familiarizes students with the methods used in studies directed to the determination of such pathways, involving sophisticated use of enzymes, organic mechanistic tools, and chemical instrumentation.
Prerequisites: A year of organic chemistry and an introductory biochemistry course.
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26:160:588
Biochemistry Laboratory (3)
Introduction to current experimental methodologies used in protein/enzyme research. Familiarizes and enables students to undertake experiments ranging from molecular biology to protein chemistry to enzyme kinetics and assay, as well as to the major tools of structural biology.
Course is open to qualified undergraduates and graduate students. Prerequisite: Either a graduate or advanced undergraduate-level theory course in biochemistry with a grade of B or better, or a year of organic chemistry, with exposure to physical chemistry preferred.
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26:160:590
Special Topics in Materials Chemistry (3)
This course will generally serve to accommodate any more specialized graduate courses in the field of materials chemistry.
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26:160:591
Biomolecular Design and Nanotechnology (3)
This course introduces the basic principles of biomolecular design and the
applications of the self-assembled nanomaterials, focusing on nucleic
acids, peptides, and proteins. Fundamental knowledge, practical
applications, and state-of-the-art research topics will be reviewed. The
course will begin with a review of the structures, properties, and cellular
functions of the four major classes of biomolecular. The main content
of this course will be the development of structural nucleic acid
nanotechnology, design and modelling of programmable biomaterials, DNA
computing and molecular programming, and DNA/RNA/Protein based
nanomachines and devices. Some of the tools for structural design can be
used as general scientific figure drawing of 3D models. Upon successful
completion of this course, students will acquire the knowledge of
biomolecular self-assembly, learn the usage of 3D graphics software, and
have a holistic view of interdisciplinary research between materials,
biochemistry, computation, engineering, and nanotechnology.
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26:160:601,602
Seminar in Advanced Topics in Chemistry (2,2)
Research topics currently under investigation. Seminars presented by faculty, distinguished outside speakers, and advanced-level students.
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26:160:701,702
Research in Chemistry (BA,BA)
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26:160:800
Matriculation Continued (E1)
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Programs, Faculty, and Courses 
