Pharmaceutical Chemistry 715

30:715:306 Pharmaceutical Chemistry (3) Principles of organic and inorganic pharmaceutical analysis. Lec. 3 hrs. Prerequisites: 01:160:311; 01:640:135; 01:750:161; 01:960:401. Hu

30:715:360 Pharmaceutical Biochemistry (2) Introduction to drug interaction in basic biochemical processes. Includes enzyme inhibitors, antimetabolites, and detoxification enzymes. Prerequisite: 11:115:301. LaVoie

30:715:409-410 Medicinal Chemistry I,II (3,3) Study of organic medicinal and pharmaceutical compounds, with special emphasis on the correlation of structural and physicochemical properties with biological activity. Prerequisite: 01:694:301 or 30:718:320. LaVoie, Rice.

30:715:412 Radiopharmaceuticals (2) Overview of the field of nuclear pharmacy and how it is utilized in disease diagnosis and therapy. Expands on prior background in pharmacology, pathophysiology, and pharmaceutics by providing additional examples to illustrate the concepts of drug distribution and metabolism as related to radiopharmaceuticals. Special attention given to the topics of designing radiopharmaceuticals and the regulations and methods for handling and administration. Safety consideration and nuclear chemistry covered in depth. Prerequisite: Fourth-year standing.

30:715:450 Drugs: Structure and Function (3) Provides a survey of the major pharmaceutical agents in clinical use. Emphasis is placed on the influence of chemical structure in the elicitation of pharmacological effects. Prerequisite: Undergraduate organic chemistry. Open only to nonpharmacy undergraduate students. LaVoie, Rice.

30:715:451 Medicinal Chemistry: Research Techniques and Principles (3) Basic course for students preparing to do research in medicinal chemistry. Topics covered include information management, computer methods, basic laboratory techniques, bioassay techniques, metabolism, prodrugs, and quantitative structure-activity relationships. Prerequisite: Undergraduate organic chemistry. Rice

30:715:452 Principles of Drug Design (3) Topics covered include identifying new drug leads, drug absorption and distribution, pharmacomodulation, enzymes and receptors as targets, peptidomimetics, computer-aided drug design, and combinatorial chemistry. Prerequisite: Undergraduate organic chemistry. Hu

30:715:453 Herbal Medicines and Nutraceuticals (2) Introduction to basic aspects of natural products chemistry as well as mechanisms associated with absorption, distribution, metabolism, and excretion of endogenous compounds and xenobiotics. Topics covered include disease states wherein herbal medicines and nutraceuticals have been suggested as having beneficial effects. LaVoie

30:715:495,496,497,498 Problems in Pharmaceutical Chemistry (BA) Undergraduate research in pharmaceutical chemistry. Prerequisite: Permission of instructor. No more than two semesters of problems courses may be used to satisfy degree requirements.