Signal Transduction (2)
Biology, pharmacology, and molecular biology of the cell cycle.
Ryazanov. Prerequisite: Permission of instructor.
Hormones and Their Receptors (2)
Modern theories of hormone action at the cellular and molecular levels. Familiarity with biochemistry, cell biology, and molecular biology is advisable.
Chen, Fondell. Prerequisite: Permission of instructor.
Molecular Response to Therapeutic DNA Damage (2)
A literature-based seminar course
focused on aspects of DNA repair, recombination, and replication as they relate
to pharmacological intervention.
Shen, Xia. Prerequisite: Permission of instructor.
Cancer Pharmacology (2)
Mechanisms of actions of antitumor agents, design and discovery of anticancer drugs, and discovery of basic signaling mechanisms that constitute the targets of molecules used for cancer therapy. Novel strategies for cancer drug discovery.
Jin. Prerequisite: Permission of instructor.
Genetics in Pharmacology (2)
Genetic strategies in understanding drug mechanisms and in the search for new pharmaceutically active agents. Some familiarity with genetics advisable.
Lobel, Walworth. Prerequisite: Permission of instructor.
Genomics in Cancer Therapeutics (3)
The application of genomics for target discovery using DNA microarrays, target identification for cancer therapeutics based on abnormalities in the cancer cell versus the normal cell, and noninvasive imaging of tumors. Gene therapy and differentiation therapy strategies for attacking the tumor cell based on knowledge gained from functional genomics of the tumor cell.
Sabaawy, Pine. Prerequisite: Permission of instructor.
Drug-Target Interactions (2)
Basic principles of nucleic acid biology, protein-nucleic acid interactions, RNA-catalyzed reactions, and chromatin with an emphasis on the relationships between these subjects with pharmacology.
Gartenberg, Gu. Prerequisite: Permission of instructor.
Cellular and Molecular Pharmacology: Principles of Drug Action and Targeting (3)
Molecular basis of pharmacologic selectivity, drug targets, adaptive responses to drugs, disposition of drugs, and genetic and molecular approaches to drug therapy.
Fondell. Prerequisites: Permission of graduate director and instructor.
Research in Pharmacology (BA,BA)