 |
BME
Teaching Facility. The first floor of
the Biomedical Engineering (BME) building is designated for the classrooms and teaching laboratory
space. This facility serves as the focus of biomedical engineering educational
and training activities on the Rutgers campus.
The first floor occupies auditorium and classroom facilities for student
instructions, teaching laboratories in molecular and cell biology, biomechanics,
and bioinstrumentation, student computer laboratories, and student reading room
and student society room.
BME Research
Facilities. Biomedical engineering has research facilities located on the second and third floor. Each
floor contains three self-contained tissue culture rooms. Each room is equipped with four temperature
controlled water-jacketed incubators, three biosafety cabinets, a refrigerator/freezer, tabletop centrifuge, inverted microscope, upright microscope, and
water bath.
In addition, the lab
is equipped with inverted and upright microscopes, a digitized fluorescence
microscopy station, a fluorescence activated cell sorter, an autoclave, and
cryopreservation facilities. A confocal microscope, housed in the basement of
the building is also available for our experimental use. The cell and tissue
engineering laboratory is thus suitable for mammalian tissue culture, cell
function analysis, cell separation, and protein expression evaluation. The cell
and tissue analysis and characterization lab contains a full complement of
biochemical and molecular biological equipment including vertical and
horizontal gel boxes, power supplies, a spectrophotometer, a gel imaging and
analysis workstation, several microcentrifuges, a -80°C freezer, and all necessary
biochemicals and electrophoresis supplies needed for protein and nucleic acid
separation and analysis. This facility also contains three biosafety cabinets and a
light cycler for nucleic acid isolation, purification, amplification, and
general PCR technology. In addition, a separate bacterial culture and analysis
laboratory contains a bacterial culture incubator and independent centrifuges
and electrophoresis gel boxes. These laboratories are thus equipped for dynamic
evaluation of cells and tissues from the macroscopic and microscopic levels to
molecular analysis of protein and gene expression.
Optical Imaging and Microscopy Laboratories. The lab has optical coherence
tomography and laser scanning confocal microscopy instruments which can be
customized for imaging in vivo or ex vivo cells and tissues. The lab is equipped with an 8' x 4' vibration
isolated optical table, four networked PCs, a fiber-optic polisher, and general
purpose test and measurement equipment including power supplies, a function
generator, and an oscilloscope.The lab
is also equipped with an inverted microscope, Zeiss Axiovert 200M with DIC 63x NA 1.4 oil, and 20x NA 0.75, Phase
40, 20, 10x and Fluorescence: FITC/GFP, TRITC, YFP, DAPI capabilities.The microscope has also been customized for
central dark field/optical scatter imaging for sizing and morphological
assessment. The high-resolution microscopy core facility also has a
motorized Nikon Eclipse TE2000-S epi-fluorescence microscope, with X-Cite® 120Q
illuminator.Three fluorescence filter
blocks are available, enabling UV (340-380 nm), blue (465-495 nm), and yellow excitation
(540-580 nm).Objectives for 4x, 10x,
20x, 40x, and 100x magnification are installed, with additional differential
interference contrast optics.
BioMEMS and
Microfabrication Laboratory. This laboratory integrates micro- and nanotechnology
within various engineering disciplines with life sciences and medical
applications, which are rapidly converging to spawn new platforms for
point-of-care diagnostics, biomedical imaging, and regenerative therapies, creating
a highly technical and thoroughly collaborative biomedical engineering
environment. The laboratory supports research, training, and education to
prepare the next generation of scientists and engineers. It maintains a fully
equipped 1,000-square-foot clean room microfabrication facility housed within the
BME building with photolithography, physical vapor deposition, plasma etching,
and other capabilities.
Stem Cell Biology and Bioengineering Laboratory. This laboratory is equipped for all cellular, histological, and molecular
recombinant DNA techniques, with dedicated microscope room for imaging
analysis. A
modern animal facility is available in the basement of the BME building
for rodent animal model research. It is equipped with surgical areas and a biosafety
cabinet. Major equipment items include: PCR machine for
recombinant DNA applications; BTX ECM 830 electroporator for in vivo/ovo
electroporation experiments; Thermo 620E cryostat for tissue sectioning; fluorescence
stereomicroscope (Leica M16FA); injection station for mouse and chick embryos;
epifluorescence upright microscope (Zeiss Axio Imager M1) for image data
analysis.
The Biomechanics and Rehabilitation Engineering
Laboratory (BREL). The BREL lab is specifically interested in topics of neurorehabilitation
and motor control. Major projects within the lab investigate novel tools for
the rehabilitation of chronic stroke, cerebral palsy, and spinal cord injury,
as well as characterization of aspects of manual and pedal motor control in
normal and afflicted subjects.
|
|
