The following courses have minimum prerequisites for undergraduate degrees in biochemistry, biology, chemistry, or microbiology with a concentration in genetics, organic chemistry, general biochemistry, or general microbiology.
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16:681:501
(F) Microbial Life (3)
Molecular aspects of origin of life, microbial evolution, properties and synthesis of the major biological polymers, transport phenomena, metabolic pathways and regulation, cellular control mechanisms, virology, applied immunology, pathogenic microbiology, and food and industrial microbiology.
Haggblom, Kerkhof, Vetriani
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16:681:502
(S) Molecular Genetics (3)
Prokaryotic and eukaryotic molecular genetics. Bacteria, bacteriophage, yeast, nematodes, Drosophila, plants, and mammals.
Vershon. Prerequisites: 16:115:501, 502.
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16:681:520
(F) Microbial Biochemistry and Molecular Biology (3)
Survey of the biochemical activities unique to microorganisms emphasizing the similarities and differences between prokaryotic and eukaryotic organisms; consideration of the genetic regulation and practical importance of these biochemical capabilities. Topics include methanogenesis, toxins, biodegradation, microbial transformations, and secondary metabolites.
Antoine. Prerequisites: 16:115:511,512, or equivalents; 16:681:521.
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16:681:521
(S) Microbial Physiology and Metabolism (3)
Microbial responses to environment with particular emphasis on nutrition and biochemistry. Enzymology and metabolic pathways of microorganisms. Metabolic diversity and regulation.
Antoine. Prerequisites: 16:681:501, 16:115:511,512, or equivalents.
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16:681:530
(S) Introduction to Molecular Medicine (3)
Application of molecular and cell biology to a wide variety of human diseases; recent advances in understanding basic mechanisms.
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16:681:543
(S) Current Concepts of Immunology (3)
Organization and evolution of the immune system, genetic basis of generation of diversity, MHC gene structure and function, development and selection of lymphocytes, lymphocyte activation, and the regulation of immune tolerance.
Shi. Offered every two years.
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16:681:544
(S) Medical Microbiology and Immunology (4.5)
Bacteria and human cells in culture. Biochemical correlations. Comparative cytology, metabolism, genetics, regulation of protein synthesis and enzyme function, immunology, virology, and medical microbiology. Principles governing mechanisms of human disease emphasized.
Prerequisite: Permission of instructor.
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16:681:545
(S) Medical Microbiology and Immunology Laboratory (1)
Experiments in the isolation, identification, and growth kinetics of bacteria; bioassay methods; organelle biogenesis; human karyotyping; diagnostic bacteriology; immunological methods; animal cell culture and virology.
Corequisite: 16:681:544. Open to medical students only.
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16:681:555
(F) Molecular Virology (3)
Detailed consideration of fundamental physical-chemical properties, schemes of classification, genetics, and modes of replication of selected animal viruses.
Stollar. Prerequisite: 16:681:501 or equivalent.
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16:681:572
(F) Microbial Ecology and Biodiversity (3)
Qualitative and quantitative methods for the study of microbial communities. Ecological determinants. Characteristics of aquatic and terrestrial ecosystems. Biogeochemical cycles and energy flow. Microbial interactions and community structure.
Barkay
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16:681:580
(F) Fundamentals of Molecular Genetics (3)
Basic mechanisms of information storage in and retrieval from nucleic acids; organization of prokaryotic and eukaryotic genomes; mechanisms of DNA replication; transposable genetic elements; and transcriptional and translational control of gene expression. Designed to provide necessary background for advanced molecular genetics courses.
Prerequisites: Genetics; 16:115:511,512.
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16:681:585
(S) Cancer Molecular Biology (3)
Emphasis on the molecular, cellular, and genetic bases for cancer. Oncogenes and tumor suppressor genes. Signal transduction and cell cycle control in cancer cells. Metastasis. Diagnosis and therapy. Recent understanding of the molecular basis of selected human cancers. Lectures and critical discussion of the current literature.
Axelrod
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16:681:601
Advanced Topics in Microbiology and Molecular Genetics (BA)
Special topics of current interest. Writing a prelim and grant proposal.
Vershon
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16:681:608
Teaching Techniques in Microbiology and Molecular Genetics (2)
Guidance and practical experience in the teaching of microbiology and molecular genetics.
Prerequisite: Open only to matriculated students in the graduate program in microbiology and molecular genetics.
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16:681:611,612,613,614
Laboratory Rotation in Microbiology and Molecular Genetics (2,2,2,2)
Half-semester research projects of interest to the student in faculty laboratories.
Prerequisite: Written approval of program director. Open only to matriculated students in the graduate program.
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16:681:641,642
Independent Studies in Microbiology and Molecular Biology (BA,BA)
Library research project normally leading to a nonthesis essay for master's degree candidates.
Prerequisites: Permission of faculty adviser and program director.
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16:681:681
Seminar in Molecular Genetics and Microbial Physiology (1)
Topics in molecular medicine. Informal critical description and discussion of current literature and concepts.
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16:681:683
Seminar in Virology, Immunology, and Pathogenic Microbiology: Yeast Genetics (1)
The application of fungal systems to molecular and cellular biology--yeast genetics. Informal critical description and discussion of current literature and concepts.
Kinzy, Vershon
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16:681:685,686
Seminar in Applied, Environmental, and Industrial Microbiology (1,1)
Informal critical description and discussion of current literature and concepts.
Vetriani
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16:681:688
Seminar in Computational Molecular Biology: Molecular Networks (1)
Recent advances in computational molecular biology selected from the following areas: genomics, bioinformatics, structural biology, image analysis, pattern formation, and molecular evolution.
Axelrod
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16:681:701,702
Research in Microbiology and Molecular Genetics (BA,BA)
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