Medicinal Chemistry: Research Techniques and Principles (3)
Basic course for students preparing to do research in medicinal chemistry. Information management, computer methods, basic laboratory techniques, and principles of medicinal chemistry.
Rice. Prerequisites: 01:160:305,306, or equivalent.
Principles of Drug Design (3)
The basic principles of how new drugs are discovered with emphasis on lead identification, lead optimization, classification and kinetics of molecules targeting enzymes and receptors, prodrug design and applications, as well as structure-based drug design methods and combinatorial chemistry.
Hu. Prerequisites: 16:160:305,306, or equivalent.
Strategies and Tactics in Synthetic Medicinal Chemistry (3)
Design of syntheses for complex organic medicinal agents. Preparation of series of analogs for structure-activity investigations.
Rice. Prerequisite: 16:160:503 or equivalent.
Drugs: Structure and Function (3)
A survey of the major pharmaceutical agents in clinical use. Emphasis on the influence of chemical structure in the elicitation of pharmacological effects.
LaVoie. Prerequisites: 01:160:305,306, or equivalent.
Heterocycles in Medicinal Chemistry (3)
Properties, reactions, and synthesis of the major classes of heterocyclic compounds, including sugars, which comprise the majority of drugs in clinical use.
Rice. Prerequisite: 16:160:503 or 504 or equivalent.
Laboratory Rotation in Medicinal Chemistry (3)
Students gain familiarity with the instrumentation and research facilities of the department by participating in research projects in the laboratories of two or three faculty members.
Restricted to first-year graduate students.
Analytical Medicinal Chemistry (3)
Fundamental concepts of analytical chemistry applied to drug discovery and development. Analysis of small and large molecules in the pharmaceutical industry.
Independent Research Proposal (3)
The student must prepare a research proposal (NIH format) on a topic not directly related to his or her research project. Following completion of the written proposal, the student is required to defend the proposal to his or her dissertation committee.
Seminar in Medicinal Chemistry (1,1)
Students prepare and present a discussion of a recent topic in medicinal chemistry.
Special Topics in Medicinal Chemistry (3,3)
Selected topics in medicinal chemistry.
Independent Study in Medicinal Chemistry (3)
No more than 3 credits may be taken as part of a student's program. Independent library research into special topics in medicinal chemistry arranged under the supervision of a faculty member.
Current Topics in Medicinal Chemistry (3,3)
Selected current topics in medicinal chemistry presented in seminar format.
Nonthesis Master's Programmatic Study in Medicinal Chemistry (3)
Literature review of small research project; final critical essay to
be presented to a faculty committee of three members.
Research in Medicinal Chemistry (3,3)
Thesis or dissertation in medicinal chemistry under the supervision of a faculty member.